Opioid Induced Hyperalgesia

Opioid Induced Hyperalgesia

Opioid Induced Hyperalgesia

Opioid-induced hyperalgesia (OIH).

BACKGROUND AND OBJECTIVES Opioids are commonly used for pain control; however, they can cause hyperalgesia. The reason why this can happen is not known. The objective of this review was to describe the mechanisms, factors implicated, and drug modulation. CONTENTS The factors implicated in the development of opioid-induced hyperalgesia (OIH), such as duration of use, dose, and type of opioids ...

Opioid Induced Hyperalgesia

Introduction Pain is one of the main reasons that people seek medical attention, and it is estimated to affect tens of millions of Americans. Chronic pain management commonly includes the use of opioid type medications. This is in spite of that fact that this class of drugs has well known adverse effects including the development of dependence, tolerance, and addiction. Recently, however, a tro...

Opioid-Induced Hyperalgesia

The use of opioids in the treatment of chronic non-cancer pain has escalated significantly in recent years. Long-term opioid use is problematic for many reasons, first: there is no evidence to support the long-term effectiveness of their use, second, opioids are well-known to be misused and abused among patients of all ages, and finally, opioids are associated with adverse events including opio...